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Journal Articles

Ubiquitin-SUMO tag-team wrestles acute promyelocytic leukemia

Alfred C.O. Vertegaal
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (6): e202504010.
https://doi.org/10.1083/jcb.202504010
Published: 09 May 2025
View articletitled, Ubiquitin-SUMO tag-team wrestles acute promyelocytic leukemia
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Journal Articles

A multifunction murine Col4a1 allele reveals potential gene therapy parameters for Gould syndrome

Mao Mao, Yoshihiro Ishikawa, Cassandre Labelle-Dumais, Xiaowei Wang, Yien-Ming Kuo, Uma B. Gaffney, Megan E. Smith, Carlie N. Abdala, Matthew D. Lebedev, William J. Paradee, Douglas B. Gould
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (6): e202409153.
https://doi.org/10.1083/jcb.202409153
Published: 25 April 2025
View articletitled, A multifunction murine Col4a1 allele reveals potential gene therapy parameters for Gould syndrome
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Includes: Supplementary data
Journal Articles

PML mutants from arsenic-resistant patients reveal SUMO1-TOPORS and SUMO2/3-RNF4 degradation pathways

Ellis G. Jaffray, Michael H. Tatham, Barbara Mojsa, Anna Plechanovová, Alejandro Rojas-Fernandez, Julio C.Y. Liu, Niels Mailand, Adel F.M. Ibrahim, Graeme Ball, Iain M. Porter, Ronald T. Hay
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (6): e202407133.
https://doi.org/10.1083/jcb.202407133
Published: 16 April 2025
View articletitled, PML mutants from arsenic-resistant patients reveal SUMO1-TOPORS and SUMO2/3-RNF4 degradation pathways
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Includes: Supplementary data
Journal Articles

Rhythmic TDP-43 affects RNA splicing of USP13, resulting in alteration of BMAL1 ubiquitination

Jianlan Gu, Mingming Yang, Liti Zhang, Yuxiao Liu, Ruolan Yan, Danmin Pan, Xiaowei Qian, Hanjing Hu, Dandan Chu, Chen Hu, Fei Liu, Hengxiang Cui
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (5): e202405142.
https://doi.org/10.1083/jcb.202405142
Published: 09 April 2025
View articletitled, Rhythmic TDP-43 affects RNA splicing of USP13, resulting in alteration of BMAL1 ubiquitination
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Includes: Supplementary data
Journal Articles

ESCRT-I and PTPN23 mediate microautophagy of ubiquitylated tau aggregates

Yusen Men, Shoshiro Hirayama, Shinpei Ao, Yasuyuki Sakurai, Yuri Shibata, Megan Lo, Yusuke Sato, Shigeo Murata
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (6): e202406120.
https://doi.org/10.1083/jcb.202406120
Published: 08 April 2025
View articletitled, ESCRT-I and PTPN23 mediate microautophagy of ubiquitylated tau aggregates
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Includes: Supplementary data
Journal Articles

Structural insights into the coupling between VCP, an essential unfoldase, and a deubiquitinase

Lauren E. Vostal, Noa E. Dahan, Matthew J. Reynolds, Lily I. Kronenberg, Tarun M. Kapoor
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (5): e202410148.
https://doi.org/10.1083/jcb.202410148
Published: 14 March 2025
View articletitled, Structural insights into the coupling between VCP, an essential unfoldase, and a deubiquitinase
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Includes: Supplementary data
Journal Articles

Cytoplasmic ribosomes on mitochondria alter the local membrane environment for protein import

Ya-Ting Chang, Benjamin A. Barad, Juliette Hamid, Hamidreza Rahmani, Brian M. Zid, Danielle A. Grotjahn
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (4): e202407110.
https://doi.org/10.1083/jcb.202407110
Published: 06 March 2025
View articletitled, Cytoplasmic ribosomes on mitochondria alter the local membrane environment for protein import
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Journal Articles

TanGIBLE: A selective probe for evaluating hydrophobicity-exposed defective proteins in live cells

Yasuyuki Iwasa, Sohtaroh Miyata, Takuya Tomita, Naoto Yokota, Maho Miyauchi, Ruka Mori, Shin Matsushita, Rigel Suzuki, Yasushi Saeki, Hiroyuki Kawahara
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (3): e202109010.
https://doi.org/10.1083/jcb.202109010
Published: 15 January 2025
View articletitled, TanGIBLE: A selective probe for evaluating hydrophobicity-exposed defective proteins in live cells
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Includes: Supplementary data
Journal Articles

Differential impacts of ribosomal protein haploinsufficiency on mitochondrial function

Agustian Surya, Blythe Marie Bolton, Reed Rothe, Raquel Mejia-Trujillo, Amanda Leonita, Qiuxia Zhao, Alia Arya, Yue Liu, Rekha Rangan, Yasash Gorusu, Pamela Nguyen, Can Cenik, Elif Sarinay Cenik
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (3): e202404084.
https://doi.org/10.1083/jcb.202404084
Published: 09 January 2025
View articletitled, Differential impacts of ribosomal protein haploinsufficiency on mitochondrial function
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Includes: Supplementary data
Journal Articles

RACK1 MARylation regulates translation and stress granules in ovarian cancer cells

In Special Collection:
Cancer Cell Biology 2025
Sridevi Challa, Tulip Nandu, Hyung Bum Kim, Xuan Gong, Charles W. Renshaw, Wan-Chen Li, Xinrui Tan, Marwa W. Aljardali, Cristel V. Camacho, Jin Chen, W. Lee Kraus
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (2): e202401101.
https://doi.org/10.1083/jcb.202401101
Published: 06 January 2025
View articletitled, RACK1 MARylation regulates translation and stress granules in ovarian cancer cells
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Includes: Supplementary data
Journal Articles

Synaptic sabotage: How Tau and α-Synuclein undermine synaptic health

Valerie Uytterhoeven, Patrik Verstreken, Eliana Nachman
Journal: Journal of Cell Biology
J Cell Biol (2024) 224 (2): e202409104.
https://doi.org/10.1083/jcb.202409104
Published: 24 December 2024
View articletitled, Synaptic sabotage: How Tau and α-Synuclein undermine synaptic health
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Journal Articles

PINK1 controls RTN3L-mediated ER autophagy by regulating peripheral tubule junctions

Ravi Chidambaram, Kamal Kumar, Smriti Parashar, Gowsalya Ramachandran, Shuliang Chen, Susan Ferro-Novick
Journal: Journal of Cell Biology
J Cell Biol (2024) 223 (12): e202407193.
https://doi.org/10.1083/jcb.202407193
Published: 18 November 2024
View articletitled, PINK1 controls RTN3L-mediated ER autophagy by regulating peripheral tubule junctions
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Includes: Supplementary data
Journal Articles

Preserve or destroy: Orphan protein proteostasis and the heat shock response

Asif Ali, Sarah Paracha, David Pincus
Journal: Journal of Cell Biology
J Cell Biol (2024) 223 (12): e202407123.
https://doi.org/10.1083/jcb.202407123
Published: 15 November 2024
View articletitled, Preserve or destroy: Orphan protein proteostasis and the heat shock response
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Journal Articles

Rapid turnover of CTLA4 is associated with a complex architecture of reversible ubiquitylation

In Special Collection:
Immune Cell Biology 2025
Pei Yee Tey, Almut Dufner, Klaus-Peter Knobeloch, Jonathan N. Pruneda, Michael J. Clague, Sylvie Urbé
Journal: Journal of Cell Biology
J Cell Biol (2024) 224 (1): e202312141.
https://doi.org/10.1083/jcb.202312141
Published: 15 October 2024
View articletitled, Rapid turnover of CTLA4 is associated with a complex architecture of reversible ubiquitylation
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Includes: Supplementary data
Journal Articles

Feedback control of the heat shock response by spatiotemporal regulation of Hsp70

Rania Garde, Annisa Dea, Madeline F. Herwig, Asif Ali, David Pincus
Journal: Journal of Cell Biology
J Cell Biol (2024) 223 (12): e202401082.
https://doi.org/10.1083/jcb.202401082
Published: 20 September 2024
View articletitled, Feedback control of the heat shock response by spatiotemporal regulation of Hsp70
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Includes: Supplementary data
Journal Articles

Integrated stress response activator halofuginone protects mice from diabetes-like phenotypes

Shashank Rai, Maria Szaruga, Aleksandra P. Pitera, Anne Bertolotti
Journal: Journal of Cell Biology
J Cell Biol (2024) 223 (10): e202405175.
https://doi.org/10.1083/jcb.202405175
Published: 16 August 2024
View articletitled, Integrated stress response activator halofuginone protects mice from diabetes-like phenotypes
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Includes: Supplementary data
Journal Articles

Mitochondrial-derived compartments remove surplus proteins from the outer mitochondrial membrane

Zachary N. Wilson, Sai Sangeetha Balasubramaniam, Sara Wong, Max-Hinderk Schuler, Mitchell J. Wopat, Adam L. Hughes
Journal: Journal of Cell Biology
J Cell Biol (2024) 223 (11): e202307036.
https://doi.org/10.1083/jcb.202307036
Published: 13 August 2024
View articletitled, Mitochondrial-derived compartments remove surplus proteins from the outer mitochondrial membrane
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Includes: Supplementary data
Journal Articles

Determining how many cells to average for statistical testing of microscopy experiments

Adam Zweifach
Journal: Journal of Cell Biology
J Cell Biol (2024) 223 (8): e202401074.
https://doi.org/10.1083/jcb.202401074
Published: 26 June 2024
View articletitled, Determining how many cells to average for statistical testing of microscopy experiments
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Includes: Supplementary data
Journal Articles

Dipeptidyl peptidases and E3 ligases of N-degron pathways cooperate to regulate protein stability

Adi Shimshon, Karin Dahan, Mor Israel-Gueta, Diana Olmayev-Yaakobov, Richard T. Timms, Aizat Bekturova, Yaara Makaros, Stephen J. Elledge, Itay Koren
Journal: Journal of Cell Biology
J Cell Biol (2024) 223 (8): e202311035.
https://doi.org/10.1083/jcb.202311035
Published: 14 June 2024
View articletitled, Dipeptidyl peptidases and E3 ligases of N-degron pathways cooperate to regulate protein stability
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Includes: Supplementary data
Journal Articles

Proteasome gene expression is controlled by coordinated functions of multiple transcription factors

Jennifer E. Gilda, Asrafun Nahar, Dharanibalan Kasiviswanathan, Nadav Tropp, Tamar Gilinski, Tamar Lahav, Dina Alexandrovich, Yael Mandel-Gutfreund, Soyeon Park, Shenhav Shemer
Journal: Journal of Cell Biology
J Cell Biol (2024) 223 (8): e202402046.
https://doi.org/10.1083/jcb.202402046
Published: 20 May 2024
View articletitled, Proteasome gene expression is controlled by coordinated functions of multiple transcription factors
Open the PDF for Proteasome gene expression is controlled by coordinated functions of multiple transcription factors in another window
Includes: Supplementary data