Skip Nav Destination
Article
A conserved role for centriolar satellites in translation of centrosomal and ciliary proteins
Centriolar satellites are cytoplasmic particles found concentrated near centrosomes and the base of cilia in vertebrate cells whose functional contribution has long been unclear. Here, Pachinger et al. present a model for satellites not as transport modules but as sites of translation specifically of centrosomal and ciliary proteins.
Report
Structure of the microtubule-anchoring factor NEDD1 bound to the γ-tubulin ring complex
The γ-TuRC is recruited to microtubule-organizing centers by NEDD1. Muñoz-Hernández et al. report cryo-EM structures revealing how NEDD1’s C terminus forms an α-helical tetramer that docks onto the γ-TuRC without inducing major conformational changes in the complex, compatible with CDK5RAP2 binding and γ-tubulin ring closure.
